Fine Structure of Reovirus Type 2

Structure and function of the reovirus genome.

INTRODUCTION ................ ................................ 483 DISCOVERY OF REOVIRUSES .............................................. 483 STRUCTURE OF THE REOVIRUS PARTICLE .................. ............. 484 REOVIRUS GENOME ................................................ 484 PROTEINS OF REOVIRUS ................................................ 486 INFORMATION CONTENT OF THE 10 REOVIRUS G...

Fine Structure of the Iridescent Virus Type I Capsid

The structure of the iridescent virus type I was examined using negative staining technique. After storage for r to z months at 4 °C or treatment with chloroform, the icosahedral capsid breaks up into its structural elementspentagons and triangles, each consisting of 31 and 55 subunits respectively. When such a preparation is centrifuged through a linear sucrose gradient (Io to 4o%), 5 zones ar...

Observations on the Fine Structure of Type 5 Adenovirus

Since the first observation with the electron microscope of intranuclear virus-like particles in sections of tissue culture cells infected with adeno-virus (1), numerous later studies of similar material have established certain morphological features of this agent (2-5). The particles have been reported to be round or ellipsoid and an inner body and outer limiting membrane have been described ...

Mechanisms of Development of Insulitis with Abnormal Glucose Tolerance in Reovirus Type 2-infected Mice

Growth characteristics of reovirus type 2: actinomycin D and the synthesis of viral RNA.

Reoviruses have been determined to be relatively large in size, 700-775 A in diameter; icosahedral in shape; possessing an inner membrane of unknown function and composition;l-4 and containing an unusual double-helical RNA structure of high molecular weight which is relatively resistant to RNase.5' 6 Cell cultures infected with reoviruses contain pale-green perinuclear inclusion bodies (acridin...